Start with your producers, or plants (grasses, flowers, etc.). Then your 1st level consumers (herbivores), like grasshoppers, mice, etc. Then your second level producers (carnivores and omnivores) that eat the herbivores (like birds). And keep going, knowing each of the levels get eaten by each other. 10% of energy is transferred in each level. An example might be...
Grass > Mice > Hawk > Vulture
I believe the correct answer is the last option. If people with down syndrome live long enough, they almost invariably develop alzheimer's disease. It is a mental disease that causes permanent memory loss this due to degeneration of the brain.
Abusing the free will to have an access to drugs (the pills) and cigarettes.