Use what you know about the bcl-2 family of genes (which includes the ced-9 gene in C. elegans) to predict the outcomes of the s
ituations described below. Select three of the below. a. In C. elegans, overexpression of ced-9 during embryonic development leads to the survival of cells that would normally undergo apoptosis.b. In human cells, underexpression of bcl-2 is associated with uncontrolled cell growth that leads to a type of cancer called follicular lymphoma.c. In humans with follicular lymphoma, a potential therapeutic would be to increase the expression of bcl-2 in the cancerous cells.d. In humans, cells that express high levels of bcl-2 are more susceptible to apoptosis.e. In humans, cells that express high levels of bcl-2 are less likely to undergo apoptosis.f. In human cell lines, scientists can manipulate the cells to force the expression of bcl-2 to prevent apoptosis.
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