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Explanation:
Answer:
The protein may not be able to function if an error occurs during transcription.
Explanation:
Explanation: mRNA is formed during transcription. If the error in the transcription occurred, the mRNA produced will be a temporary one and ultimately degraded.
When a hairpin loop forms in the nascent mRNA: The hairpin will destabilize the interaction and possibly lead to transcriptional termination.
Transcription in prokaryotes like E. coli is terminated either by a rho-dependent process or a rho-independent process. Intrinsic termination is controlled by the specific sequences of RNA .
When the termination process starts, the transcribed mRNA forms a stable secondary structural hairpin loop, also known as a stem-loop. Several uracil nucleotides follow this RNA hairpin. The uracil and adenine connections are exceedingly weak. NusA, a protein attached to RNA polymerase, attaches to the stem-loop structure so firmly that it momentarily stalls the polymerase.
The polymerase is pausing at the same time that the poly-uracil sequence is being transcribed. The RNA-DNA duplex can unwind and separate from the RNA polymerase because the weak adenine-uracil interactions reduce the energy of destabilization for the RNA-DNA duplex. Overall, transcription is terminated by the modified RNA structure.
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Answer:
A) purine
Explanation:
There are two ways for the synthesis of purines and pyrimidines:
- de novo synthesis-from basic simple units
- "recycling" synthesis-reuse of metabolites
Purines are synthesized directly on ribose sugar, in segments.
Pyrimidines are attached to the ribose after the synthesis of the base.
5-Phosphoribosyl-1-pyrophosphate (PRPP). is used for the synthesis of purine (ribose 5-phosphate reacts with ATP to form ribonucleotide).
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