Generally, mutations result in reduced protein function or no protein function. A mutation with reduced function is called a leaky mutation because some of the wild-type function “leaks” through into the phenotype. A mutation that results in no protein function is called a null mutation
A hypotonic state of the
bladder, or conduct and duration of labor and peripartum bladder management, and
the use of epidural anesthesia may all contribute to overflow incontinence.
Overflow incontinence is characterized
by uncontrolled, spontaneous passing of urine because of an overfull bladder.
They are variables that cannot be changed or are purposefully not changed in an experiment.
