Loss of Rb, an important part of the G1-S transition checkpoint, can result in uncontrolled cell cycle progression and cancer. All of the following would mimic loss of Rb except constitutively active Ras GTPase activating protein. Correct answer: letter E.
Constitutively active Ras GTPase activating protein would not mimic loss of Rb, because it would not directly result in uncontrolled cell cycle progression.
<h3>What is Retinoblastoma (RB)?</h3>
Rb is an important tumor suppressor protein that works to inhibit cell cycle progression by preventing the activation of E2F transcription factors. Constitutively active Ras GTPase activating protein would not directly interfere with the Rb-E2F pathway, which is necessary for uncontrolled cell cycle progression and cancer.
Learn more about the cell cycle:
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Helps to reduce pollution in a community
Answer:
1.Karam (Karma) Harvest Festival in India
2.Kashmir Rice Harvest Festival
3.Onam Festival
4.Nuakhai
5.Baisakhi
Explanation:
Answer: The DNA on the paternal copy of the chromosome will be methylated at the imprinting center, while the DNA on the maternal copy of the chromosome will not be methylated in this region.
Explanation:
Chromosomes are DNA structures associated with proteins such as histones. They are found in the nucleus of cells and contain genetic information for the development and functioning of an organism. Human beings are diploid, meaning that they possess two copies of each of the 23 chromosomes (a total of 46).
Gametes, which are sex cells such as the sperm (produced by the male) and the egg (produced by the female) that are haploid. This means that they possess only one chromosome of each pair. During fertilization, a male gamete fuses with a female gamete to generate a zygote, which will give rise to a new human being. <u>This new individual will possess half of the genetic material from its father and half from its mother. Thus having a total of 46 chromosomes, 23 from each parent</u>.
Genetic imprinting modulates gene expression by chemical modification of DNA and/or modification of chromatin structure. Often, genetic imprinting causes a gene to be expressed only on the chromosome inherited from one of the parents. One example of imprinting is DNA methylation, which is a process by which methyl groups are added to DNA. <u>Methylation modifies DNA function when found in the promoter gene, repressing gene transcription. This means that a methylated gene will not be expressed</u>, that is, it will not produce a protein encoded by that gene. So, if a region of DNA is imprinted in the sperm cell, the paternal chromosome inherited from this sperm will be methylated in the genes of the offspring. And the offspring will only express the maternal copy inherited, which will not be methylated.
The deer eat grass. Its droppings, which eventually decompose into the ground, provide minerals and vitamins to the plant roots. This food is vital for it so the plant remains alive and can produce oxygen which is essential for the deer and grass is also a food source for him too.
