Answer: A
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Answer:
A. The chromatin near cis-regulatory sequences will be more closed and there will be less transcription.
Explanation:
In the presence of histones, the cis-regulatory sequences of DNA like promoter, enhancers etc. are not exposed. The function of the histone acetyltransferases (HATS) is to cause chromosome decondensation i.e. removal of histones from the DNA so that transcription of the DNA could occur. Histone acetyltransferases (HATS) cause acetylation of lysine amino acid of the histone proteins. Acetyl group is negatively charged so the acetylation of histone proteins leads to the removal of their positive charge which ultimately leads to the decrease in the interaction between N terminal of histones and negatively charged phosphate group of the DNA molecule. As soon as histones are removed from the DNA where cis-regulatory sequences are located, the DNA becomes accessible for transcription.
But here a drug has been added which blocks the activity of histone acetyltransferases (HATS) in cancer cells. So it is quite evident that in these cells, histones will not get removed from the cis-regulatory sequences of DNA so the DNA will be more closer or tightly packed as a result of which less transcription will occur.
Answer:
Option A
Explanation:
Thyroid is primarily caused by lack of iodine but there are other reasons as well that lead to increased size of the thyroid gland. Some of these reason is
a) over- or underproduction of thyroid hormones
b) Nodules in the glans
Some times, due to overstimulation immune system itself attack the thyroid gland thereby producing excess thyroxine and hence causing the thyroid to swell
Thus, Option A is correct
Answer:
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secondary succession
Explanation:
Large, low intensity disturbances, such as plowing in conventional agriculture, result in moderate amounts of succession, where species can survive in the soil and quickly recolonize areas after a disturbance. This type of succession is often called secondary succession
