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Mexico was essentially broke. The country was racked by financial instability as the war began in 1846. America's blockade of Mexican ports worsened an already difficult situation, as Mexico couldn't import and export goods, or levy taxes on imports.
The correct answer is option C: someone diagnosed with smallpox.
The person that would have been most grateful for the work of 19th-century scientist Edward Jenner, would be someone diagnosed with smallpox because Jenner was who discovered the first vaccine against the smallpox virus. Moreover, this disease that was widely spread in the 18th century and killed many people.