Griffith used two types of bacteria in his experiment
1. R-type: it was non-virulent and cause no disease in mice
2. S-type: It was virulent and cause disease in mice which lead to death.
However when heat killed S-type was applied no disease was occurred in mice. Then he mixed heat killed S-type and live R-type and injected it into mice. He was expecting that no disease will be caused in mice.
Results However, mice was died.
Conclusion He was confused from this experiment. But later it was confirmed by other scientists that DNA from heat killed S-type was shifted to R-type. the progeny which formed from this transfer of DNA were virulent and cause the death of mice.
significance
It was concluded from this experiment that DNA is a hereditary material which transfer characters from parents to offspring.
Blood groups are inherited from both parents. The ABO blood type is controlled by a single gene (the ABO gene) with three types of alleles inferred from classical genetics: i, IA, and IB. The I designation stands for isoagglutinogen, another term for antigen.