The gizzard is used for the preparation of digestion. The food is ground by the action of the muscular walls and also the gravel inside the gizzard.
I am pretty sure the answer is increase and increase. Because enzymes are affected by changes in pH. The most favorable pH value - the point where the enzyme is most active - is known as the optimum pH. Extremely high or low pH values generally result in complete loss of activity for most enzymes.
The role of 3tc in inhibiting hiv reproduction is to interfere with enzyme trancriptase since it has a similar shape to the c nucleotide of DNA.Reverse trancriptase pick up 3tc molecule which led to termination of DNa further thus block reproduction of HIV.
One is climate change I think
