The 'Encomienda' system supported the plantation-based labor where the Natives were used as slaves and they were to convert them to Christianity. Later this system was gradually replaced by African slaves.
The Europeans attempted to change Native American beliefs and worldviews on basic social issues such as religion, gender roles, family, and the relationship with the environment. This attempt at changes led to Native resistance and conflict. EX: Spanish Mission System
Spanish colonists initiated slavery to the Africans and With the rise of sugar cultivation as an export product, sparniards increasingly utilized enslaved Africans for labor on commercial plantations. in this case, the Spanish relation with Africans was just exploitation.
The Silk Road of ancient China is an example of cultural diffusion <em><u>occurring at a result of a trade.</u></em> Although the route began in about 138 B.C. as a means for China to export silk fabric -- a rare and valuable commodity -- trade along the Silk Road greatly promoted the exchange of products, ideas and practices between Oriental and Western civilizations.
Some slaves risked everything to escape and join the British side during the American Revolution in order to gain their freedom. This was also a major motivation of slaves who sought to fight for the American side as well.