Answer:
Answer explained
Explanation:
a. Overexpression of Axl receptor tyroxine kinase correlates with the decresed patient's overall survival and hence it's inhibition is under process.
AXL TKI BMS777607 treatment increased AXL protein levels after 24 h as observed by Western blot and flow cytometry analysis. Mechanistically, this inhibition-induced AXL cell surface accumulation was neither associated with epigenetic modifications, nor altered transcriptional and translational regulation. Hence this later increased the glycosylated protien abundance in kinase dead mutant. The kinase function blockaging resulted in impaired internalisation which finally incresed the level of proliferation.
An alternative technique may exist in linkage of Axl Tkl to a degradation machinery recruitment unit .
b. Mendelian disorders like cystic fibrosis results from error in the given DNA sequence which can be autosomal dominant and recessive both and also X or Y linked. Mutated gene results in the Mendelian disorders. Whereas in cancer there can be mutation or proliferation of the given cells in a specific area. In cancer cells there is 2.5 times more the mRNA present while 6.2times the DNA and hence the detection and diagnosis automatically becomes difficult as in Mendelian disorders only single sequence needs to be studied at a time .
The correct option is D.
Wind has some advantages which makes it suitable as a source of energy but it also possesses some disadvantages which reduces its potentials as a viable source of energy. For instance, large expanse of land will be needed to construct wind farms and this may not be feasible especially in populated areas. Another disadvantage is that electricity production will be depended on the availability of wind, when there is no wind, there will be no electricity.
The root tip allows the plant to grow deeper into the soil
It could be reflex or instinct, most likely reflex
Answer:
that cannot be changed because of it dominancy
