B. When Rosa parks refused to give up her seat on a bus
Ferdinand Magellan was the first (at least his crew) to successfully lead an expedition to circumnavigate the world. (he died on the voyage, but ~3 sailors made it back i believe, forgot the number of sailors, but very little)
hope this helps
According to quiz-let, the answer is now ending isolation from its isolation from "Europeans hermit". So I would choose B.