Question

The second messenger, phosphatidylinositol 3,4,5-trisphosphate (PIP 3) is generated by the action of the enzyme _______ on phosphatidylinositol 4,5-bisphosphate (PIP 2).
A. mTOR kinase
B. phosphatidylinositide (PI) 3-kinase
C. protein kinase A
D. protein kinase C

Answer 1

Answer:

Protein kinase C.

Explanation:

Protein kinase C may be defined as the enzymes that controls the function of proteins by phosphorylation of the specific substrate. This enzyme mainly phosphorylate at the hydroxyl group at Serine and Threonine amino acids.

The protein kinase C enzyme acts on the substrate phosphatidylinositol 4,5-bisphosphate (PIP 2). This result in the formation of secondary messenger like phosphatidylinositol 3,4,5-trisphosphate (PIP 3) and diacyglycerol (DAG). They shoe the similar transduction pathway as shown by phospholipase C.

Thus, the correct answer is option (D).