Osteoporosis is the disease of the low bone mass and most often caused by the increase in the bone resorption that is not in sufficiently compensated for by the corresponding increase in the bone formation. As result gut-derived serotonin (GDS) inhibits the bone formation, we can asked whether hampering its is biosynthesis that could treat the osteoporosis through the anabolic mechanism (that is, by increasing bone formation).
We can synthesized and used the LP533401, a small of molecule inhibitor of the tryptophan hydroxylase-1 (Tph-1), the initial enzyme in the GDS biosynthesis. or the Oral administration of this small molecule once daily for up to the six weeks that acts as prophylactically or therapeutically, in the dose-dependent manner, to treat the osteoporosis in the ovariectomized the rodents because of an isolated increase in the bone formation. These results that provide a proof of the principle that have inhibiting the GDS biosynthesis that could become a new anabolic and treatment for osteoporosis.
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Answer:
circulatory system
Explanation:
Oxygen and nutrients are taken to body parts by the Circulatory System (also named Vascular System)
B.<span>the coded blueprint for life</span>
Answer:
Qualitative
Explanation:
There's two kinds of observation in the scientific method: quantitative and qualitative.
Quantitative is like physical measurement, actual numbers and such. Such as height, weight, etc.
Qualitative is like color, descriptions, shape etc.
Therefore, I think answer should be Qualitative.