Answer:
Pyruvate dehydrogenase (PDH) is a very high molecular weight mitochondrial multienzyme complex.It includes three types of enzymes that need the participation of five coenzymes to develop their activity, three of them catalytic cofactors (TPP, lipoamide, FAD) and two stoichiometric (NAD and CoA). Two enzymes involved in regulating its activity are also part of the enzyme complex.
Explanation:
PDH is a multienzyme complex formed by multiple copies of three catalytic proteins (E1, E2 and E3) and other structural and regulatory (phosphatase, kinase). It requires, in turn, different coenzymes (thiamine, lipoic acid) for its proper functioning. Given its enormous importance at a key point in energy production, it is highly regulated.
E1 depends on thiamine pyrophosphate and catalyzes 2 stages: 1) decarboxylation of pyruvate, forming a hydroxyethyl-thiamine-diphosphate intermediate; 2) reductive acetylation of the lipoyl group, covalently linked (amide) to E2.
E2 catalyzes the transfer of the acetyl group to CoA (3). E3 regenerates the oxidized lipoyl, transferring its electrons first to FAD and then to NAD.
Answer:
It is important to have more than one piece of evidence to make sure that the evidence is actually evidence. Or in other words, that the evidence is proven true. With only one piece of evidence, you can't be fully sure if calculations were correct, if the source was trustworthy, etc.
Multiple evidence is kinda like double checking math problems. If you don't do it, you can't be 100% certain the answer is correct.
It helps with the optic nerve, if you give me options i can help answer. Sorry if I didnt help :)
Salt marshes are diverse ecosystems because there are resources from both
Answer:
Conservation of energy, principle of physics according to which the energy of interacting bodies or particles in a closed system remains constant. The first kind of energy to be recognized was kinetic energy, or energy of motion. In certain particle collisions, called elastic, the sum of the kinetic energy of the particles before collision is equal to the sum of the kinetic energy.
Explanation:
