They were conquered by the Spanish.
The attack on Fort Sumter, April 13th, 1861 culminates in the war led by the conflicts and tensions in the South, more specifically with the surrender of General Robert Anderson that set defense in Charleston Harbor in South Carolina. The fort took fire from artillery and bombardments by the Confederate State armies. The Fort couldn't stand long a defense, so it surrendered shortly after in April 1861 eventually leading to the formal declaration of war between the States in the North, loyal to the Constitution, and the southern states.. which were advocating for the split.
A missionary is someone who is sent on a religious, especially one sent to promote Christianity in a foreign country. William Carey