Answer:
<em>the answer is chemical property since acid is involved.</em>
<span>The nurse should explain that cigarette smoking is not suggested for clients like you that have vascular problems.
</span><span>Smoking will increase the risk of developing intermittent claudication. Stop smoking will be beneficial since it could prevent the disease progress into rest pain It also reduces the risk of heart attack.</span>
Answer:
1. P120 is degraded in the 26S proteasome
2. The 26S proteasome has a major role in protein degradation and is critical for protein homeostasis
3. Cell cycle and DNA replication are cellular processes regulated by the Ras and NFkB pathways
Explanation:
The proliferation-associated nucleolar protein (p120) is a protein known to be expressed during the interphase of the cell cycle, specifically in G1 and early S phase, where any problem with DNA replication trigger a checkpoint, i.e., a molecular cascade of signaling events that suspend DNA replication until the problem is resolved. In mammalian cells, the 26S proteasome is responsible for catalyzing protein degradation of about 80% (or even more) of their proteins. The 26S proteasome acts to degrade rapidly misfolded and regulatory proteins involved in the cell cycle, thereby having a major role in protein homeostasis and in the control of cellular processes. It is for that reason that inhibitors that block 26S proteasome function have shown to be useful as therapeutic agents in diseases associated with the failure of protein degradation mechanisms (e.g., multiple myeloma). The NF-κB are highly conserved transcription factors capable of regulating different cellular processes including, among others, cellular growth, inflammatory responses and apoptosis. Moreover, the MAPK/ERK pathway is able to transduce different signals received on the cell surface to the nucleus. The MAPK/ERK pathway is activated when a singling molecule binds to a cell receptor which triggers a signaling cascade that ends when a transcription factor induces the expression of target genes, ultimately producing a response in the cell (for example, the progression through the cell cycle).
Answer:
X-linked recessive
Explanation:
The trait is a sex-linked trait because the daughters are not colorblind, but the sons are. We know this its recessive because the daughters have inherited the mother's X chromosome that has the colourblindness trait, but are not colorblind because the father's X does not have the colourblindness trait. The sons are colourblind because they inherited the X from their mother with the colourblindnese trait and a Y from their father. The colourblindness trait or normal vision trait is not carried on the Y, so the mother's X chromosome's trait is expressed.
Sorry if it's confusing i tried my best to explain it
Replication is the process where DNA molecules copies itself to form another DNA molecule during cell division. it involves several enzymes which includes DNA helicase, the enzyme that unwounds the DNA double helix. RNA primase, it is an enzyme that creates an RNA primer. DNA polymerase, it is the enzyme that matches and lays down nucleotides to form the new DNA daughter. DNA ligase joins the Okazaki fragments by catalysing the formation of phosphodiester bond.
