<span>A drug used to treat CML, imatinib, binds to the active site of Abl kinase. Why does this drug work to treat this type of cancer?
</span><span>B) By binding to the active site, the drug prevents the ability of Abl kinase to bind to its substrate.
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Imatinib works against CML by binding close to the ATP binding site of bcr-abl. The binding results to the<span> locking in of the bcr-abl to a closed or self-inhibited conformation and inhibiting the enzyme activity of the protein </span><span>semi-competitively.</span>
Internal fertilization protects<span> the </span>fertilized egg<span> or embryo from predation and harsh environments</span>
Hey there!
I believe answer is B2 or Beta 2
Answer:
A. Chipmunks sleeping underground through the winter
Explanation:
A seasonal change in the behavior of a living organism is a change that occurs every year at a particular time. The reasons for the occurrence of such changes are so that the organism has advantage in survival in the environment. In this case we have the chipmunk that sleeps underground through the winter. We have an animal which exhibit a seasonal change every year, during the winter period. The reason for this is that the chipmunks have very quick metabolism, so if they are active during the winter they will starve because of lack of food. Instead, the chipmunks have evolved to hibernate during the winter, thus slowing down the work of their hurt during the winter and sleep, until the spring comes.
