<em>Denaturation involves the breaking of many of the weak linkages, or bonds (e.g., hydrogen bonds), within a protein molecule that are responsible for the highly ordered structure of the protein in its natural (native) state. Denatured proteins have a looser, more random structure; most are insoluble.</em>
I think it is carbohydrates
The sickle form of the hemoglobin gene is created when an adenine nucleotide is changed to a thymine. ... That single amino acid replacement in the -globin protein alters the shape and the chemistry of the hemoglobin molecule, causing it to polymerize and distort the red blood cell into the sickle shape.
Answer is A. I kid chemistry a while back but I am pretty certain it is A.
