Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
The dorsal surface in for legged animals is called superior
It all depends on the trait. If the dominant is more common that the recessive trait then it is more likely to a dominant trait in the gene pool. But if the recessive trait is more common in the gene pool then you will have a recessive trait. Does this make sense? Let me know if I'm right!
Tretinoin is a naturally occurring metabolite of retinol in the retinoid class, including natural and synthetic analogues. It is the acid form of vitamin AIt acts on cell growth and differentiation. Its main use is the treatment against acne thanks to its keratolytic and anti-inflammatory properties. Tretinoin is also used in the treatment of acute myeloid leukaemia type 3 (AML 3).
SIDE EFFECTS:
Among the expected effects, side effects may occur. Signs of an allergic reaction include: hives, difficulty breathing, swelling of the face, lips, tongue or throat;
It should be known that tretinoin can make you more sensitive to the sun, so use sunscreen every day, and wear protective clothing outdoors.
Cholesterol and triglycerides should be done before and during treatment because this drug could increase their values
Some patient with leukaemia treated by tretinoin has suffered from The syndrome of retinoic acid which is characterized by fever, dyspnea, acute respiratory distress...
Answer: The subphases of interphase (in order) are G1, S and G2.
Explanation:
