Did not like Western influence--traders brought Christianity and Western culture with them that the Chinese and Japanese did not like.
Western traders often came with goods and Christian missionaries. The influence of Christianity influence Asian cultures and was viewed as a negative to the culture of China and Japan. The isolation occurred as an attempt to remove Western influence from the countries.
A it led to conflicts with the Republican Congress on ape.x
Many Northerners were happy that free states now had more representatives in Congress. However, many were also upset with the Fugitive Slave law.
This law, that was part of the Compromise of 1850, made it so that any slave that escaped to the North must be returned to their owner in the South. Many northerners thought this was unfair and did not want to follow this law. This is because almost all northern states had outlawed slavery by this point and time.
The Northern Renaissance was also closely linked to the Protestant Reformation with the resulting long series of internal and external conflicts between various Protestant groups and the Roman Catholic Church having lasting effects.