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butalik [34]
3 years ago
7

Many human genes are known to have homologs in the mouse genome. One approach to investigating human hereditary disease is to pr

oduce mutations of the mouse homologs of human genes by methods that can precisely target specific nucleotides for mutation.
Part A: Numerous studies of mutations of the mouse homologs of human genes have yielded valuable information about how gene mutations influence the human disease process. In general terms, describe how and why creating mutations of the mouse homologs can give information about human hereditary disease processes. Select the two correct answers.

a. Mice are also diploids organisms.
b. Mice and human genetic disorders have arisen from conserved and related evolutionary processes.
c. Mice are useful for performing experimental manipulations that are not possible in the case of humans.
d. Mice have a much smaller genome than humans.

PART B: Despite the homologies that exist between human and mouse genes, some attempts to study human hereditary disease processes by inducing mutations in mouse genes indicate there is little to be learned about human disease in this way. How and why might the study of mouse gene mutations fail to produce useful information about human disease processes?

a. Every human gene has a homolog in the mouse genome, enabling mice to always provide useful information on the human disease process.
b. In cases where the physiology or genetics of mice and humans differ, mutations in a mouse homolog to a human disease gene may not provide useful information on the human disease process.
c. The differences in anatomy and physiology might hide or change development and symptoms of disease.
Biology
1 answer:
AURORKA [14]3 years ago
3 0

Answer:

Part A....B

Part B....C

Explanation:

It should be understood that Mice are always first used to clinical test especially for drugs or other things that are supposed to be for human use, this is because Mice and human genetic disorders have arisen from conserved and related evolutionary processes. Therefore, when the clinical trial or test produces a positive result in the Mice, it is almost certain that the result will be the same in human.

Now in part B. When the result result is different, it might be because of the differences in anatomy and physiology might hide or change development and symptoms of disease. And that is the reason why, the result of a particular drug differs from person to person.

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kiruha [24]

Answer:

I'll inform them that the possibility of all their future children/offspring being phenotypically sickle-celled is very high.

Explanation:

Sickle cell is an inherited disease condition in which the red blood cells of the blood loses its shape and hence, dies or gets broken down. It has to do with the blood genotype of an individual. There are three major types of blood genotypes in humans namely: AA, AS, and SS. SS is the recessive genotype that codes for the sickle cell trait.

Hence, a human with the sickle cell trait has a genotype- SS. Therefore, according to this question, a man and a woman, each with sickle-cell trait (SS), were planning to marry, This will mean that both the man and the woman will always produce a gamete with S allele, which will combine to form an SS offspring. In other words, all of the offsprings of this man and woman will be sickle-celled.

7 0
2 years ago
Please help me with this it’s due today
uranmaximum [27]

Answer:

The correct answer is - 0 m/s.

Explanation:

In this position-time graph or distance-time graph, there are three different part that shows three different velocities one in increasing as it moves from a lower position in relative to time and one is stationary and the third is decreasing.

'Straight lines' on a distance-time graph suggest that the movement of the object is constant. During 'Part B' of the journey the object travels 0m in 3s. It is stationary for 3 seconds so the velocity will be zero as well.

3 0
2 years ago
Scientists isolate cells in various phases of the cell cycle. They find a group of cells that have times more dna than g1 phase
ratelena [41]

Answer:

in the S phase of the cell cycle

Explanation:

<em>Scientists isolate cells in various phases of the cell cycle. They find a group of cells that have 1.5 times more DNA than G1 phase cells. The cells of this group are _____.</em>

The cell cycle has two main stages which is the interphase and the M phase.

While the M phase is characterized by active division, the interphase consists of G0 phase which is entirely a resting phase for cells that do not need to divide ordinarily, G1 phase which is a phase for cell drowth and development, S phase which is a phase for DNA synthesis or replication and G2 phase which is a phase for protein synthesis.

Hence, cells in the S phase and G2 phase of the cell cycle are expected to have more DNA than cells in the G0 and G1 phase.

<em>Essentially, the amount of DNA is doubled in the S phase. Therefore, if the cell group have 1.5 times more DNA than G1 phase cells, it means the cells are still in S phase.</em>

<em />

5 0
3 years ago
Is this the correct answer to this question?
Pepsi [2]
I think yes but im just answering to ask a question sorry
8 0
2 years ago
Read 2 more answers
How many chromosomes do human reproductive cells contain ?
9966 [12]

Answer:

23 chromosomes.

Explanation:

Human gametes have 23 chromosomes.Reproductive cells (gametes) are haploid - they have half the number of chromosomes as a body (somatic) cell. HOPE IT HELPS:)

3 0
2 years ago
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