<h2>Fatty acid oxidation </h2>
Explanation:
- Activation of fatty acids (palmitate) occurs in the cytoplasm where fatty acids are activated to fatty acyl CoA, reaction catalysed by an enzyme called fatty acyl CoA synthetase
- A specialized carnitine carrier system catalyze transportation of activated fatty acid from cytoplasm to matrix of mitochondria, where carnitine system consists of three proteins:
- Carnitine acyl transferase I located in outer membrane of mitochondria catalyze transfer of carnitine to fatty acyl CoA and produce fatty acyl carnitine
- Carnitine translocase facilitate passive diffusion of fatty acyl carnitine from inter membrane space to matrix located in inner membrane
- Carnitine acyl transferase III located in inner mitochondrial membrane at matrix phase catalyze transfer of CoA to fatty acyl carnitine and regenerate fatty acyl CoA
Hence, the cytosolic and mitochondrial pools of CoA are thus kept separate, and no radioactive CoA from the cytosolic pool enters the mitochondria
Answer:
Explanation:
Vaccinations need a large amount of the population to work effectively. With people not getting vaccinated they are putting the majority of the people at risk of an outbreak of that.
