OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
Answer:Clauses: Shira yawned, I am tired today Phrases: the old orange cat, bright red and shiny, jumped over the puddle
Explanation:
It can make your paper more appealing to readers, and/or more informative for the readers as well.
The symbolism of the new cloak in this excerpt is - the new cloak represents Odysseus's transformation from a weary traveler to the returning hero.
He spent many years on the sea, far from his family and loved ones, and he became old and tired. This new cloak is his transformation - he is a hero now, and he has come back to Ithaca to rule again.
Dear friends, today we are gathered to say goodbye to Don Quixote, a great man, whom I have sweet memories and that will never be erased from my mind. Don Quixote was a dreamer, intelligent and courageous. Many called him crazy and throughout his life he had to live with the humiliation and mockery of his closest friends who saw him as insane for living his own convictions. I confess that I was one of those and I regret not having given my attention to him before. I believe his friends would also be sorry if they heard him without judgment, as I did when I decided to be his faithful squire.
Don Quixote was a knight inside and out, he dared to keep the wonderful world of fantasy in our cruel reality. He was noble, kind, generous and passionate ... in love with life, books, adventures, landscapes and fantasy. Today he promotes his latest adventure and while we say goodbye I ask him not to be sad to continue the walk without me, because I know that when we meet again, our trips will be even more profitable.
