<span>i think Comparative morphology
i could be wrong tho</span>
Cytokinesis did not occur properly during the cell cycle. Ie. the splitting of the cytoplasm was not done. hence the genetic materials are separated in two distinct nuclear envelope. if this continued of non-cytokinesis,then more distinct nuclei can occur
Teperature
Ph level
Substrate concentration
Not sure if these are physical but hope it helped.
The answer is that they treat bacterial infections.