The Rome in 1400s was a different city than the old Rome of the Roman empire. They were a blooming city of the late medieval period which had problems given the spreading plague at the time. This time also marked a slow transition towards the renaissance which also lead to different advances in life and society.
In 1400s, Rome was troubled by things such as social upheavals, collapsing institutions, <span>contact cutoff with China, the plague, and many other things that caused problems for the state. </span>