The major downfall of the Articles of Confederation was simply weakness. The federal government, under the Articles, was too weak to enforce their laws and therefore had no power. The Continental Congress had borrowed money to fight the Revolutionary War and could not repay their debts.
(If I'm wrong, PLEASE let me know in the comments)
The Industrial Revolution had a positive impact on women because it allowed women to move from a domestic sphere environment a public sphere environment, it allowed women to be more politically engaged, and due to independent wages, gave them a sense of independence.