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Natasha_Volkova [10]
3 years ago
15

On average, errors occur in DNA synthesis only once in every ten billion nucleotides incorporated. Which of the following does N

OT contribute to this high fidelity of DNA synthesis? (A) Complementary base-pairing between the nucleotides (B) Tightening of the DNA polymerase around its active site to ensure correct pairing before monomer incorporation (C) Proofreading by the 3'-to-5' exonuclease activity of the enzyme to correct mispairing even after monomer incorporation (D) A strand-directed mismatch repair system that detects and resolves mismatches soon after DNA replication (E) None of the above
Biology
1 answer:
Nesterboy [21]3 years ago
8 0

Answer:

(E) None of the above

Explanation:

All of the answers contribute to the high fidelity of DNA synthesis.

Accuracy of the DNA replication is achieved thanks to various mechanisms such as:

  • DNA polymerase activity (high processivity)-ability of the enzyme to copy long stretches of DNA
  • DNA polymerase proofreading-ability to recognize its own mistakes and fix them
  • Cell's surveillance-cell monitors its DNA status, checks for the damage
  • Mismatch Repair-cell contain repair machinery which recognizes DNA helix deformities,  removes and replaces the portion containing the mismatch etc.

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