The answer is True. You're welcome in advance
The correct answer is: D) nullification.
Jefferson's Kentucky Resolution (drafted in 1798) introduces the theory of nullification. This means that states, individually, can judge a central government law and declare it unconstitutional if they desire to do so.
The triangular trade route or the Silk Road
Think about that expression -- crossroads of culture. The early West was something of a plethora of human beings, with people of all breeds and flavors a) travelling, such as the Mormon (Latter-day Saint) pioneers, b) going for gold (Gold Rush), c) running a business, etc. Another factor to consider is that the pioneers (the Mormons) had their numbers bolstered by people from England, Ireland, Scotland, throughout the US and other places, in consequence of missionary efforts by the Latter-Day Saint Church, and in response to the call of their prophet to "gather to Zion." With that amalgamation of people it's not hard to see why, at least in the early settlements, it's called a "crossroads of culture," due to the hundreds of types of variety present. Of course, other immigrants and families moved to the west other than the Mormons. I don't mean to imply the Mormons were alone in their endeavor.