Nucleoside Reverse Transcriptase Inhibitors (NRTIs) are the first class of antiretroviral drugs that function by competing with the naturally occurring nucleosides within the cell that the virus would use to build the DNA chain.
What these nucleosides lack is a substance that is required to elongate the DNA chain. Hence, it outcome make the DNA chain to shorten and inability to insert itself into the host DNA thereby causing the Virus by not been able to reproduce.
Nucleoside Reverse Transcriptase Inhibitors (NRTIs) also block reverse transcriptase enzymatic function and further stops the completion of synthesis of the double-stranded viral DNA, thus preventing the Virus from multiplying.
