Answer:
The basement membrane or basal lamina on which the epithelium form, made by extracellular matrix.
Explanation:
The basement membrane is the layer underlies all epithelia that is made up extracellular matrix secreted by the epithelium cells that provide structural support to the structure of epithelia.
It forms the barrier between epithelial tissues therefore once a epithelial cancer penetrate this basement membrane it will spread to all underlying tissues.
Thus, the correct answer is - The basement membrane or basal lamina on which the epithelium form, made by extracellular matrix.
The basement membrane is form of extracellular matrix that underlies all epithelia. It provides structural support to epithelia and forms a mechanical connection between epithelia and underlying connective tissue.
The basement membrane, or basal lamina, is a sheet of proteins and other substances to which epithelial cells adhere and that forms a barrier between tissues.
Epithelial cancers may have the ability to penetrate through the basement membrane and spread to underlying tissues.
