The correct answers are I and IV
There are three main effects of complement :
1. Lysis of cells such as bacteria and tumor cells.
2. Generation of mediators that participate in inflammation and attract neutrophils to the site of infection, an event called chemotaxis.
3. Opsonization i.e. enhancement of phagocytosis.
Lysis of pathogens by complement involves the insertion of a special substance called the membrane attack complex into the cell membrane of the pathogen which disrupts or punctures the membrane as a result of which water and electrolytes enter the pathogen and it dies.
Generation of mediators known as C5a and C567 complex attract neutrophils.
Answer:
a. substantia nigra
b. substantia nigra (it is repeated)
Explanation:
Parkinson's disease is a neurodegenerative disease that is caused by the death of neurons that release the neurotransmitter dopamine in the <u>substantia nigra</u>, or locus niger, -a region of the brain that regulates brain circuits that give the 'orders' to initiate voluntary movements- .
The lack of this neurotransmitter leads to the occurrence of the main symptoms suffered by patients: decreased movements, muscle stiffness, postural instability and tremor. These failures are generated by the abnormal way in which neurons work in the absence of dopamine through a mechanism that is not known in depth.
It is the second most frequent neurodegenerative disease, after Alzheimer's disease, with a prevalence of 2% in people over 65 years. The characteristic symptoms of stiffness, bradykinesia and tremor are associated with losses of neurons in the substantia nigra and dopamine depletion in the striatum. There are large cytoplasmic inclusions, called Lewy bodies, which are the pathological mark of the disease and appear predominantly in neurons that contain melanin of the nigra substance. Genetic studies in a subgroup of families with Parkinson's disease with autosomal dominant inheritance found a locus on chromosome 4q-21 23 and a mutation in the gene that encodes a synaptic protein, α-synuclein.
Distribution of phenotypes within a population may be impacted by different types of natural selection. These types of selection include;
Directional selection involves a change in the environment shifts of phenotypes observed. Example is the giraffe neck-length, where the length got longer and longer over time to reach the leaves at the top of trees.
Stabilizing selection , this is a selection where an average phenotype is favored. example is number of eggs laid by birds such that too many eggs will be a waste of energy because some chicks would starve.
Disruptive selection is a selection where individuals with an average value of a trait are affected most while those with values below average are affected least. Example small individuals are capable of hiding from predators while big individuals can not fit in the hiding place but instead will fight with predators.
I would say down wind side but I'm not 100% sure
Answer:
Osteoblasts
Explanation:
Cells that secrete protein fibres in bones are called osteoblasts.
I hope this helps.