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larisa [96]
3 years ago
12

The p53 gene is responsible for helping build a protein inside of cells that plays a critical role in repairing damaged DNA or

Biology
1 answer:
Mkey [24]3 years ago
8 0

Answer:

A cell that has Damaged p53 gene , A) may become Cancerous; B) may experience uninhibited and out of control cell division; C) may accumulate multiple mutation.

Explanation:

  • p53 gene is a tumor suppressor gene that encodes a polypeptide that acts as a transcription factor.
  • Mutation in p53 is associated with 50% of human cancers.
  • Loss of p53 removes DNA damage check point.
  • Mutation in p53 prevents DNA repair and the apoptosis of cells that contain irreparable damage.
  • as a result the cells may accumulate multiple mutations.
  • Since Functional p53 promotes DNA repair and arrest the cell cycle if a damaged DNA is present; any mutation in p53 may result in uncontrolled cell growth and tumor formation.
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