Question

The p53 gene is responsible for helping build a protein inside of cells that plays a critical role in repairing damaged DNA or

Answer 1

Answer:

A cell that has Damaged p53 gene , A) may become Cancerous; B) may experience uninhibited and out of control cell division; C) may accumulate multiple mutation.

Explanation:

• p53 gene is a tumor suppressor gene that encodes a polypeptide that acts as a transcription factor.
• Mutation in p53 is associated with 50% of human cancers.
• Loss of p53 removes DNA damage check point.
• Mutation in p53 prevents DNA repair and the apoptosis of cells that contain irreparable damage.
• as a result the cells may accumulate multiple mutations.
• Since Functional p53 promotes DNA repair and arrest the cell cycle if a damaged DNA is present; any mutation in p53 may result in uncontrolled cell growth and tumor formation.