The name of the enzyme RNA polymerase
To act as a catalyst in chemical reactions
The discovery of DNA, as well as understanding of its functioning and structure, may well be the most essential findings of the last century.
The impact of the discovery of DNA on medical and scientific advancement has been huge, whether it involves the manufacturing and creation of drugs to cure the deadly diseases or to identify the genes, which stimulate several of the diseases.
The understanding of DNA and its structural composition has led to the discovery of various technologies that helps in the fields like genetic testing, identifying viruses, crime investigation, production of genetically modified organisms, and various others.
Definition: "Copying of information from DNA to RNA which exit nucleus is known as transcription"
Explanation: Transcription is a vital process for living organisms, because it is a staring point for protein synthesis. It occurs inside the nucleus and is carried out by RNA polymerase enzyme. In eukaryotes RNA pol is of three types: these are RNA Pol 1, RNA Pol 2, and RNA Pol 3. In prokaryotes it is of only one type.
Steps in transcription: Transcription consists of three main steps
1. Initiation: In this step RNA pol attach to DNA template at 5 prime end in the promoter region to start the formation of complementary strand of RNA. In prokaryotes there is a region called
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Pribnow box, with the </span>consensus sequence<span> TATAAT present about 10 base pair away from site that serves as a transcription initiation. In eukaryotes the promoter region is more complex it contain activator and enhancer.
2. Strand elongation: </span><span>Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding nucleotides to the 3′ end of the growing chain.
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3. Transcription Termination:
Terminator sequences are found close to the ends of non-coding sequences. Before termination polyadenylation occurs. <span>
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