The correct answer is C. Southwest Asia
There were outposts in the Indian ocean and they traded slaves in that area as well as northern Africa. Mexico and South America had not yet been discovered while Russia was too far away to participate in anything. They traded with locals in around Egypt as well as the SEA region.
C is most likely going to be your answer.
Well isolationism is when ur isolated from everything or everyone. Ur pretty much independent to ur self.
Assuming you're referring to the Great Compromise in the United States, it was very important because it satisfied both the large and small states (in terms of population) regarding how they would be represented in Congress.