When an animal's oxygen supply is limited, bisphospoglyceric acid increases the oxygen level by acclamitization.
Acclimatization is the term used to describe the advantageous physiological changes brought on by frequent exposure to a hot climate. Increased sweating effectiveness is one of these physiological modifications. It is converted into a molecule identical to that of 2,3-bisphosphoglyceric acid (2,3BPG). A mechanism called 2,3BPG is employed to control the effective emission of oxygen from haemoglobin. As one of the processes of acclimatization, 1,3-BPG levels will rise in a patient's blood when concentration is low. Low oxygen levels increase 1,3BPG levels, which in turn increase 2,3BPG levels and change how well oxygen separates from hemoglobin.
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Water-borne diseases, including cholera, typhoid, and dysentery, are caused by drinking water containing infectious viruses or bacteria, which often come from human or animal waste. Water-washed diseases, such as skin and eye infections, are caused by lack of clean water for washing.