It would have something to do with either the economy or market
Your answer is true have a good day
Answer:
1-Infectious Eurasian diseases (For example: Smallpox)
2-Attempts of assimilation (and Manifest Destiny)
3-Relocation attempt (Indian Removal Act of 1830)
4-Diminished food supply for nomadic tribes
5-The introduction of horses and other animals to the new world (through the Columbian Exchange)
Answer: Hard Times
Explanation: I would say Hard Times, but it could also be the one about Presidential because of George Washington
C: they establish ourposts or settlementys in the region