estar because if she feels sad then she is being depressed and if she is on another place the she is being there
estar=being
Yo = soy
Tu = eres
El=es
Ella=es
Nosotros =somos
Vosotros=sois
Ellos=son
Ellas =son
The answer is #1 because está is conjugated in the él/ella/usted form and it should be in yo form.
It mean "May/Can I go to the restroom?"
