What is the rest of the question?
B, European settlers were immune to such diseases like smallpox because it came from their region, when knowledge that the native Americans were not immune and the disease was lethal to them, they started distributing blankets and clothing items that were infected with the viruses and caused a major impact on native population
I would say the 4th one
Sorry if it’s wrong
Narrowest point of land along Central America and the bodies of water helped as well
Panama Canal
War and the space race