A good time to use the "journalistic" question words is when you are writing a class essay.
Sunny~ ☺
Answer:
(Have) a nice time in Rome?
Explanation:
"You a nice time in Rome?" Doesn't make any sense because a person can't be time, they can only have time.
I think it would be To Whom It May Concern, because you don't know their relationship status (if that makes any sense)
I could be wrong though...
D) to change so as to better suit your surroundings
Definition
make (something) suitable for a new use or purpose; modify.
-become adjusted to new conditions