The answer is the second option.
The Hardy-Weinberg equation assumes that all genotypes occur with equal frequency, i<span>f selection can be quantified, relative fitness values can be calculated and used to appropriately modify the Hardy-Weinberg equation.
</span><span>Choices to this question are:
1---but if there is selection against one or more genotypes, equal frequency of all genotypes is not possible.
2----If selection can be quantified, relative fitness values can be calculated and used to appropriately modify the Hardy-Weinberg equation.
<span>3----Natural selection can influence the genotype frequencies predicted by Hardy-Weinberg, but allele frequencies are not affected.
</span>4----If it can be determined that selection favors a particular genotype, the Hardy-Weinberg equation should not be applied.</span>
