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In this study, we tested the effects of NEAA-deprived diets and checkpoint inhibitor anti-PD-1 and anti-PD-L1 in colon cancer using syngeneic mouse model (Balb/c) bearing tumors of mouse colorectal cancer cell line CT-26. Three diets were tested, including a natural rodent diet Teklad ENVIGO Global 16% Protein Rodent Diet (control 1), a formulated NEAA-complete diet COMPLETE (control 2, using amino acid mix in place of protein), and a formulated NEAA-deprived diet FTN203 (treatment, using amino acid mix in place of protein). Both COMPLETE and FTN203 have the same nutritional structures, contain 17% w/w protein equivalent, and are isocaloric. After tumor size-based randomization, these diets were provided to mice ad libitum throughout the whole test. Each of these diets was used alone or combined with anti-PD-1 antibody (i.p., twice per week for 2 weeks) or anti-PD-L1 antibody (i.v., twice per week for 2 weeks).
Explanation:
You should not leave it out longer than 1/2
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inner organizer is a person who organizes, especially the one who forms and organizes a group
Explanation:
a person whose job is to enlist employees into membership in a union
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The giant numbers painted on the airport runways stand for the airport's name and are called a heading. The runway heading consists of two numbers between 1 and 36. This means the heading is based on the compass directions with 360 representing north, 90 – east, 180 – south, and 270 – west.
A taxiway is a path for aircraft at an airport connecting runways with aprons, hangars, terminals and other facilities. They mostly have a hard surface such as asphalt or concrete, although smaller general aviation airports sometimes use gravel or grass.Taxiways can be a combination of letters and numbers, or letters alone. They are indicated on a black sign with yellow letters or a yellow sign with black letters and arrows. A black square with yellow letters and/or numbers inside signifies the plane's position on the various taxiways.
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