Answer:
C Spain was weakened by wars with Britain and France.
Explanation:
I’m assuming you’re talking about the Spaniards and the Aztecs. If not correct me and I’ll fix the answer. Basically it was, Disease (smallpox) More advanced weapons. The spanish language. Catholicism. Domestic animals, sugar, grain, and they helped end the practice of human sacrifice.
The southern colonies reliance on slave labor eventually could have caused problems because it kept the economy from developing manufacturing jobs or other jobs for the middle class.