I believe alleles for the same trait are separated from each other during the process of meiosis.
If the parietal cells in your stomach stop functioning The pH of the abdomen will rise.
Parietal cells, called oxyntic cells, are stomach epithelial cells that release intrinsic factors and hydrochloric acid (HCl). These cells are present in the stomach's gastric glands, which are situated in the fundus and body regions. Gastric acid secretion, which helps with food digestion, mineral absorption, and bacterial control, is controlled by parietal cells.
In the center of the glands in the fundus-body region of the stomach are the parietal cells. They release the intrinsic factor, a protein that binds vitamin B12, and gastric acid, or hydrochloric acid (about 0.16 M, pH 0.8). The parietal cells that are destroyed are unable to create enough stomach acid. As a result, the pH of the stomach rises, food digestion is hampered, and the risk of gastroenteritis increases.
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Answer:
by designing a drug with steric effects on BCR-ABL1
Explanation:
Chronic myeloid leukemia (CML) is a type of cancer that affects the bone marrow and blood cells. CML is characterized by the formation of the Philadelphia chromosome, a product of a reciprocal translocation between chromosomes 9 and 22. As a consequence of this translocation, an oncoprotein tyrosine kinase called BCR-ABL1 is formed. This protein (BCR-ABL1) is responsible for 95% of all CMLs. In this case, it is possible to inhibit BCR-ABL1 (and thus inhibit CML cell proliferation) by using a kinase inhibitor. Kinase inhibitors are drugs that inhibit kinase function by preferentially binding to the inactive conformation of the target enzyme. These proteins are used to treat cancer by blocking a functional site on the kinase, thereby inhibiting its function. Moreover, it is known that steric effects alter the mode and rate by which a drug interacts with a given target. In this case, a small molecule with steric effects on BCR-ABL1, i.e., capable of altering the shape (conformation) and reactivity of BCR-ABL1, might also be used to selectively inhibit BCR-ABL1.
Dr. Pringle suggests that there's only very few large herbivorous species that can survive in certain area. The reason behind his claim is that according to him there will be only enough food for few large species, so there's natural limitations in the food sources, as there should be enough to support them in order for them to survive.
On the other hand, in Mpala, there's 22 large herbivorous species, which directly contradicts Dr. Pringle's hypothesis. The reason why so many large species of herbivores an survive in Mpala and always have enough food for all of them, is that they have all specialized in eating certain types of plants or parts of plants, thus they are not direct competition to one another, and there's always enough food for all of them.
