Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
The right answer is DNA is located in the nucleus.
The genome is the whole genetic material of an organism. It contains both the coding sequences, i.e. those that encode proteins, and the non-coding sequences. In most organisms, the genome is the DNA in the cells. However, in some viruses called retroviruses (eg HIV), the genetic material is RNA.
Answer:
Nanotechnology has bring up major advances in our everyday life. For example, the use of Nanobots that are extensively used now a days in medicine to make surgeries faster and accurate. By the use of nanotechnology, major problems like cancer can be treated by using cell by cell therapy. It is also utilized in curing genetic defects. Major drug designing and drug delivery has been made easier using nanotechnology.
Nanotechnology doesn't have any visible disadvantages but there always remains a fear like introduction of some extra contaminants and toxins in the environment. But mostly i agree with use of nanotechnology for the betterment. Furthermore we don't have any more advance techniques to fight problems than this technology.
Answer:
Body functions stimulated by the parasympathetic nervous system (PSNS) include sexual arousal, salivation, lacrimation, urination, digestion, and defecation. The PSNS primarily uses acetylcholine as its neurotransmitter. Peptides (such as cholecystokinin) may also act on the PSNS as neurotransmitters. The parasympathetic nervous system is composed mainly of the cranial and sacral spinal nerves.
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