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ki77a [65]
3 years ago
5

Refer to Animation: Base Excision Repair. In the example in the animation, uracil is incorrectly paired with guanine. What is th

e effect on the DNA sequence if base excision repair does not remove the uracil and DNA replication is allowed to proceed?
Biology
1 answer:
REY [17]3 years ago
5 0
<h2>Mutation will occur </h2>

Explanation:

Base excision repair operates for small DNA damage such as deaminated bases

  • DNA glycosylase plays an important role in cleavage of glycosidic bond of abnormal base (does not cleave phosphodiester bond)
  • Uracil is incorrectly paired with guanine then mutation will occur
  • The original GC base pair will change into AT base pair(transition of GC to AT)
  • Transition is a mutation in which one purine(adenine or guanine) is substituted for other or one pyrimidine(cytosine or thymine or uracil) is substituted for other

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