The digestion of the food in humans begins in the mouth. In the mouth, the salivary amylase enzyme digests and breaks down a small amount of the starch present in the food. The digestion process begins right in the mouth. and continues till the intestine. The carbohydrates (starch) are the ones whose digestion starts in the mouth.
Hence, the blanks can be filled with 'mouth and amylase' respectively.
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Hormones -- such as melatonin and cortisol; the former signals the body to go to bed, while the latter signals for the sleeping person to wake up -- are created by physiological changes.
They are alike because both tell what was the truth about somthing.