Answer:
Watson and Crick proposed the double helical model of DNA.
Explanation:
- This model says that DNA exist as double helix. It has two polynucelotide strands running in opposite direction i.e the strands are anti-parallel.
- Each polynucleotide strand is made up of several nucleotide liknked together by phophodiester bonds.
- The two strands are not coiled upon each other but the double strand is coiled upon itself around a common axis like the spiral stair case. Here base pairs forms the stairs and backbone of two strands form railing. Back bone contains sugar and phosphate.
- The base pairing is specific, adenine always pairs with thymine and guanine always pairs with cytosine. Thus if we see any base pair, it consists of one purine and one pyrimidine.
- The two strands of DNA thus show complementary base pairing.
- The strands are held together because of hydrogen bonding between the bases in opposite strand.
- One full helical turn involves ten base pairs and the base pairs are stacked 3.4 A apart.
- This form is called as B-form of DNA.
Answer:
a.There are three signaling pathway
1- Reception in which molecule binds to receptor
2- Signal transduction in which activation of intracellular pathway and enzyme occur.
3- Cellular response in which specific response of cell occur according to receptor and ligand.
b. Three types of receptors are
1- autocrine
2- paracrine
3- endocrine.
Explanation:
autocrine receptors are signaling pathway in which cell releases its molecule and bind to its own cell receptor example cancer cells while paracrine in which ligand binds to other nearby cell receptor and it is used during development and in endocrine cell target distinct cell and travel through blood stream like hormones functioning.
Answer:
Explanation:
We present an explicit and simple approximation for the superadiabatic excess (over ideal gas) free power functional, admitting the study of the nonequilibrium dynamics of overdamped Brownian many-body systems. The functional depends on the local velocity gradient and is systematically obtained from treating the microscopic stress distribution as a conjugate field. The resulting superadiabatic forces are beyond dynamical density functional theory and are of a viscous nature. Their high accuracy is demonstrated by comparison to simulation results.
