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D.) European explorers transmitted smallpox, decimating the native people of North and South America.
The disease's affected the indigenous peoples of North and South America was that European explorers transmitted smallpox, decimating the native peoples of North and South America.
The colonists' war against the Native Americans resulted in the use of a violent strategy by the colonists to decimate the natives, which was the use of blankets and sheets contaminated with smallpox, designating biological warfare. Thus the colonists traded blankets and cloths to the natives, they, in turn, gave the natives diseases that lowered their population.
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