Answer:
Deadly disease
Explanation:
In 1521, Hernan Cortez on behalf of the Spanish crown and in the hope of finding golds in the New World invaded Aztec empire in Tenochtitlán, a location in the present day of Mexico.
Hernan Cortez and his group of soldiers and allies were able to invade and conquer the Aztec empire by various factors, some of which includes superior weapons, like guns, horses for fighting, metal armor, and deadly diseases such as smallpox, measles, and influenza
To buy and or sell merchandise
"The Santa Fe Trail was an important trail between the United States and
Mexico. People in both countries wanted to buy and sell merchandise
from each other. Merchants used the trail to make money by hauling items
to sell when they reached the end of the trail."